Christopher deCharms

Christopher deCharms is a serial entrepreneur , neuroscientist , social entrepreneur , author , inventor , and founder and CEO of Omneuron , a life sciences company focusing on new technologies for measuring and changing brain function based on groundbreaking imaging methods therein allow directive people to watch the activation or hun eigen brains ‘live’ using functional magnetic resonance imaging (fMRI). This Allows people to learn to change the patterns of hun eigen mind and mental functioneren through changing hun brain activation patterns. This work, funded by the National Institutes of Health, is in late-stage clinical trials for novel Treatments of chronic pain, depression, and anxiety. Recently deCharms has founded Brainful Inc. to bieden the Omneuron technologies to people worldwide in mobile / web for the treatment of chronic pain, Presented in 2014 at LeWeb . deCharms been killed founding president or Civizen Inc. welke is ontwikkelingslanden a new technology to stop violence and promote safety.


DeCharms has developed a set of technologies allowing patients, physicians, researchers, and subjects to Visualize and control the functioneren the brain using non-invasive methods based on real-time functional magnetic resonance imaging (rtfMRI), sea deCharms’ TED talk, and is Exploring applications of functional brain imaging. DeCharms started his research career in neurofysiologie as a graduate student and later Postdoctoral researcher in the laboratory or Professor Michael Merzenich at the UCSF Keck Center for Integrative Neuroscience. This work included recording patterns of brain activation from multiple locations in the brain, and how synthesis patterns of activation underlie perception, experience and learning.

rtfMRI training

DeCharms and a team of collaborative researchers port Explored Whether people kan learn to control patterns of activation taking place inside hun eigen brains. It was not to post leg skies to non-invasively measure brain activation in real time using neuroimaging, but recent advances in computation and neuroimaging port made this a reality using rtfMRI. Subjects’ brain activation patterns are Measured using real-time fMRI as the subjects watch from inside the scanner using virtual reality goggles, and subjects are Trained to control the patterns of activation inside hun eigen brain. This in turn leads to changes in the subjects’ mental experiences. For example, subjects learned to control port activation in brain regions associated with pain, and they ‘report a corresponding decrease in hun levels of pain. DeCharms’ team coined the term Neuroimaging Therapy in use to DESCRIBE this approach. Research on rtfMRI-based training has leg published in the scientific literature and has ook leg Broadly Covered in the popular press waaronder The New York Times , [1] BBC, NPR, Wired, Technology Review. [2] This research has leg conducted at Stanford University and more Recently at Omneuron’s 3T MRI Research Center in Menlo Park , California through funding from the National Institutes of Health .

Selected research papers

  1. deCharms, RC; Maeda, F .; Glover, GH; Ludlow, D .; Pauly, JM; Soneji, D .; Gabrieli, JD & Mackey, SC (2005). “Control over brain activation and pain learned by using real-time functional MRI” . Proceedings of the National Academy of Sciences USA . 102 (51): 18626-18631. Bibkey : 2005PNAS..10218626D . doi : 10.1073 / pnas.0505210102 . PMC  1311906 . PMID  16352728 .
  2. deCharms, RC; Christoff, K .; Glover, GH; Pauly, JM; Whitfield, S. & Gabrieli, JD (2004). “Learned regulation of spatially localized brain activation using real-time fMRI.” NeuroImage . 21 (1): 436-443. doi : 10.1016 / j.neuroimage.2003.08.041 . PMID  14741680 .
  3. Miller, KL; Hargreaves, BA; Lee, J .; Ress, D .; deCharms, RC & Pauly, JM (2003). “Functional brain imaging using a blood oxygenation sensitive steady state”. Magnetic Resonance in Medicine . 50 (4): 675-683. doi : 10.1002 / mrm.10602 . PMID  14523951 .
  4. deCharms, RC & Zador, A. (2000). “Neural representation and the cortical code”. Annual Review of Neuroscience . 23 : 613-647. doi : 10.1146 / annurev.neuro.23.1.613 . PMID  10845077 .
  5. deCharms, R. C. (1998). “Information coding in the cortex at independent or coordinated populations” . Proceedings of the National Academy of Sciences USA . 95 (26): 15166-15168. Bibkey : 1998PNAS … 9515166D . doi : 10.1073 / pnas.95.26.15166 . PMC  33,931 . PMID  9860939 .
  6. deCharms, RC; Blake, DT & Merzenich, MM (1998). “Optimizing sound features for cortical neurons.” Science . 280 (5368): 1439-1443. doi : 10.1126 / science.280.5368.1439 . PMID  9603734 .
  7. deCharms, RC; Merzenich, MM (1996). “Primary cortical representation of sounds in the coordination of action potential timing”. Nature . 381 (6583): 610-613. Bibkey : 1996Natur.381..610D . doi : 10.1038 / 381610a0. PMID  8637597 .


  1. Jump up^ Jason Pontin (2007-08-26). “Mind Over Matter with a machine’s help” . The New York Times .
  2. Jump up^ Emily Singer (2006-07-01). “Seeing Your Pain: Learning to consciously alter brain activity through MRI feedback Could help control pain and other disorders” . Technology Review .